Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression
نویسندگان
چکیده
منابع مشابه
The evolutionary history of YAP and the hippo/YAP pathway.
The Hippo/YAP pathway plays an important role in animal organ size control, which it exerts by regulating tissue proliferation and apoptosis rates as a response to developmental cues, cell contact, and density. With the ever increasing advance in genome sequencing and analysis tools, our understanding of the animal world and its evolution has greatly increased in the recent years. We used bioin...
متن کاملThe YAP Prolog system
Yet Another Prolog (YAP) is a Prolog system originally developed in the mid-eighties and that has been under almost constant development since then. This paper presents the general structure and design of the YAP system, focusing on three important contributions to the Logic Programming community. First, it describes the main techniques used in YAP to achieve an efficient Prolog engine. Second,...
متن کاملExpression of Yes-associated protein (YAP) in breast phyllodes tumor.
This study aimed to identify expression profiles of Yes-associated protein (YAP) and its phosphorylated form (pYAP) in phyllodes tumor (PT) of human breast and verify the clinical implications. We selected PTs from the pathologic archive and reviewed the histologic features (141 benign, 27 borderline, and 15 malignant). We made tissue microarray (TMA) block from the formalin-fixed paraffin-embe...
متن کاملExpression of YAP in the Skin Lesions of Lichen Planus
Objective: To explore the expressions of yes-associated protein (YAP) in skin lesions of lichen planus (LP) and normal skin. Methods: Immunohistochemistry was carried out to quantify the expression of YAP in tissues from the lesions of 30 patients with LP and 30 healthy controls. Results: In normal skin tissues, YAP was slightly expressed in the basal layers of the epidermis, and the positive r...
متن کاملYCF and YAP gene expressions in yeast cells after irradiation combined with mercury treatment
Background: All aerobically growing organisms suffer from exposure to oxidative stress, caused by partially reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are highly reactive and capable of damaging cellular constituents such as DNA, lipids and proteins. Consequently, cells from many different organisms have evolved mechanisms to protect their components...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2019
ISSN: 1465-7392,1476-4679
DOI: 10.1038/s41556-019-0433-z